Publications

Selected publications:

Jessica L. Sinka, Indira Queralta-Castillo, Lorena S. Yeung, Isabel Molina, Sangeeta Dhaubhadel and Mark A. Bernards (2024) Altered metabolism in knockdown lines of two HXXXD/BAHD acyltransferases during wound healing in potato tubers. Plants, 13(21), 2995; https://doi.org/10.3390/plants13212995

Kosma, José Graça, and Isabel Molina (2024) Update on the Regulated Biosynthesis and Structure of the Apoplastic Polymers Cutin and Suberin. Plant Physiology; accepted.

Meng Lin, Harel Bacher, Richard Bourgault, Pengfei Qiao, Susanne Matschi, Miguel Vasquez, Marc Mohammadi, Sarah van Boerdonk, Michael J. Scanlon, Laurie G. Smith, Isabel Molina Michael A. Gore (2024) Integrative multi-omic analysis identifies genes associated with cuticular wax biogenesis in adult maize leaves. G3: Genes|Genomes|Genetics; jkae241. doi: 10.1093/g3journal/jkae241

Richard Bourgault and Isabel Molina*. Compositional analysis of cutin in maize leaves (2024) In: Maize: A Laboratory Manual, edited by Candice N. Hirsch and Marna D. Yandeau-Nelson. Cold Spring Harbor Protocols, doi: 10.1101/pdb.prot108434

Regina Niñoles, Paloma Arjona, Sepideh M. Azad, Aseel Hashim, Jose Casañ, Eduardo Bueso, Ramón Serrano, Ana Espinosa, Isabel Molina, José Gadea (2023) Kaempferol-3-rhamnoside overaccumulation in flavonoid 3'-hydroxylase tt7 mutants compromises seed coat outer integument differentiation and seed longevity. New Phytologist, 238(4):1461-1478; https://doi.org/10.1111/nph.18836

Isabel Molina, Amauri Bueno, Antonio Heredia, and Eva Dominguez (2023) Editorial: Plant cuticle: From biosynthesis to ecological functions. Front. Plant Sci. 14:1154255; https://doi.org/10.3389/fpls.2023.1154255

Lin, Pengfei Qiao, Susanne Matschi, Miguel Vasquez, Guillaume P. Ramstein, Richard Bourgault, Marc Mohammadi, Michael J. Scanlon, Molina, Laurie G. Smith, Michael A. Gore (2022) Integration of GWAS and TWAS to elucidate the genetic architecture of natural variation for leaf cuticular conductance in maize. Plant Physiology, 189(4):2144–2158; https://doi.org/10.1093/plphys/kiac198

Meghan K. Rains, Christine Caron, Sharon Regan, Isabel Molina* (2022) Chemical and molecular characterization of wound-induced suberization in poplar (Populus alba x P. tremula) stem bark. Plants, 11(9): 1143; https://doi.org/10.3390/plants11091143. Paper is featured on the issue cover.

Nayana Gardiyehewa de Silva, Jhadeswar Murmu, Denise Chabot, Keith Hubbard, Peter Ryser, Isabel Molina and Owen Rowland. 2021. Root Suberin Plays Important Roles in Reducing Water Loss and Sodium Uptake in Arabidopsis thaliana. Metabolites, 11(11):735. https://doi.org/10.3390/metabo11110735

Nayana Gardiyehewa de Silva, Céline Boutin, Anna Lukina, Tamara Western, Isabel Molina, and Owen Rowland. 2021. Seed coat suberin forms a barrier against chromium (Cr3+) during early seed germination in Arabidopsis thaliana. Environmental and Experimental Botany, 191: 104632. https://doi.org/10.1016/j.envexpbot.2021.104632

Kaija Goodman, Julio Paez Valencia, Janice Pennington, Annika Sonntag, Xinxin Ding, Han-Nim Lee, Paul Ahlquis, Isabel Molina, Marisa S. Otegui. 2021. ESCRT components ISTL1 and LIP5 are required for tapetal function and pollen viability. The Plant Cell; 33(8): 2850-2868. https://doi.org/10.1093/plcell/koab132

Joan Renard, Irene Martínez‐Almonacid, Indira Queralta Castillo, Annika Sonntag, Aseel Hashim, Gaetano Bissoli, Laura Campos Jesús Muñoz‐Bertomeu, Regina Niñoles, Thomas Roach, Susana Sánchez‐León, Carmen V. Ozuna José Gadea, Purificación Lisón, Ilse Kranner, Francisco Barro, Ramón Serrano, Isabel Molina, Eduardo Bueso. 2021. Apoplastic lipid barriers regulated by conserved homeobox transcription factors extend seed longevity in multiple plant species. New Phytologist, 231(2): 679-694. https://doi.org/10.1111/nph.17399.

Maofeng Chai, Indira Queralta Castillo, Annika Sonntag, Shixing Wang, Zhili Zhao, Wei Liu, Juan Du, Hongli Xie, Fuqi Liao, Jianfei Yun, Qingzhen Jiang, Juan Sun, Isabel Molina, and Zeng-Yu Wang. 2021. A seed coat specific β-ketoacyl-CoA synthase, KCS12, is critical for preserving seed physical dormancy. Plant Physiology, 186(3): 1606–1615. https://doi.org/10.1093/plphys/kiab152.

Fakhria M. Razeq, Dylan K. Kosma, Débora França, Owen Rowland, and Isabel Molina. 2021. Extracellular lipids of Camelina sativa: Characterization of cutin and suberin reveals typical polyester monomers and unusual dicarboxylic fatty acids. Phytochemistry, 84: 12665. https://www.sciencedirect.com/science/article/abs/pii/S0031942221000121

Xue Liu; Richard Bourgault, Mary Galli, Josh Strable, Zongliang Chen, Fan Feng, Jiaqiang Dong, Isabel Molina, and Andrea Gallavotti. 2021. The FUSED LEAVES1-ADHERENT1 regulatory module is required for maize cuticle development and organ separation. New Phytologist; 229: 388-402. https://doi.org/10.1111/nph.16837

Susanne Matschi, Miguel F Vasquez, Richard Bourgault, Paul Steinbach, James Chamness, Nicholas Kaczmar, Michael A. Gore, Isabel Molina, Laurie G. Smith. 2020. Structure-function analysis of the maize bulliform cell cuticle and its potential role in dehydration and leaf rolling. Plant Direct 00: 1– 21, DOI:10.1002/pld3.282.

Pengfei Qiao, Richard Bourgault, Marc Mohammadi, Michael A. Gore, Isabel Molina, and Michael J. Scanlon. 2020. A maize LIPID TRANSFER PROTEIN may bridge the gap between PHYTOCHROME-mediated light signaling and cuticle biosynthesis. Plant Signaling & Behavior, 15:9. https://doi.org/10.1080/15592324.2020.1790824

Pengfei Qiao, Richard Bourgault, Marc Mohammadi, Susanne Matschi, Glenn Philippe, Laurie G. Smith, MichaelA. Gore, Isabel Molina, Michael J. Scanlon. 2020. Transcriptomic network analyses shed light on the regulation of cuticle development in maize leaves. Proceedings of the National Academy of Sciences USA, 117 (22) 12464-12471.

Meng Lin, Susanne Matschi, Miguel Vasquez, James Chamness, Nicholas Kaczmar, Matheus Baseggio, Michael Miller, Ethan L. Stewart, Pengfei Qiao, Michael J. Scanlon, Isabel Molina, Laurie G. Smith, Michael A. Gore. 2020. Genome-wide association study for maize leaf cuticular conductance identifies candidate genes involved in the regulation of cuticle development. G3: Genes|Genomes|Genetics, 10 (5): 1671-1683; https://doi.org/10.1534/g3.119.400884

Joan Renard, Irene Martínez-Almonacid, Annika Sonntag, Isabel Molina, José Moya-Cuevas, Gaetano Bissoli, Jesús Muñoz-Bertomeu, Isabel Faus, Regina Niñoles, Jun Shigeto, Yuji Tsutsumi, José Gadea, Ramón Serrano, Eduardo Bueso. 2020. PRX2 and PRX25, peroxidases regulated by COG1, are involved in seed longevity in Arabidopsis. Plant, Cell and Environment, 43:315–326.

Richard Bourgault, Susanne Matschi, Miguel Vasquez, Pengfei Qiao, Annika Sonntag, Caleb Charlebois, Marc Mohammadi, Michael J Scanlon, Laurie G Smith, Isabel Molina. 2020. Constructing functional cuticles: Analysis of relationships between cuticle lipid composition, ultrastructure and water barrier function in developing adult maize leaves. Annals of Botany, 125: 79-91.

Lifang Zhao, Tegan Haslam, Annika Sonntag, Isabel Molina, and Ljerka Kunst. 2019. Functional Overlap of Long-Chain Acyl-CoA Synthetases in Arabidopsis. Plant and Cell Physiology, 60(5): 1041–1054.

Meghan K. Rains, Nayana Dilini Gardiyehewa de Silva, Isabel Molina. 2018. Reconstructing the suberin pathway in poplar by chemical and transcriptomic analysis of bark tissues. Tree Physiology, 38( 3):340–361.

Maofeng Chai, Chuanen Zhou, Isabel Molina, Chunxiang Fu, Jin Nakashima, Wenzheng Zhang, Jongjin Park, Yuhong Tang, Qingzhen Jiang and Zeng-Yu Wang. 2016. A Class II KNOX gene, KNOX4, controls seed physical dormancy. Proceedings of the National Academy of Sciences USA, 113 (25), 6997-7002.

Dylan Kosma, Isabel Molina and Owen Rowland. 2015. Analysis of Suberin-Associated Root Waxes from Arabidopsis and Other Plant Species. Bio-protocol, 5(24):e1679.

Seamus Jenkin and Isabel Molina. 2015. Isolation and compositional analysis of plant cuticle lipid polyester monomers”. Journal of Visualized Experiments (JoVE), 105: e53386, doi:10.3791/53386; http://www.jove.com/video/53386.

Isabel Molina and Dylan Kosma. 2015. Role of HXXXD-motif/BAHD acyltransferases in the biosynthesis of extracellular lipids. Plant Cell Reports, 34: 587-601.

Vandana Yadav, Isabel Molina, Kosala Ranathunge, Indira Queralta Castillo, Steven J. Rothstein, Jason W. Reed. 2014. ABCG transporters are required for suberin and pollen wall extracellular barriers in Arabidopsis. The Plant Cell, 26: 3569-3588.

Fakhria M. Razeq, Dylan K. Kosma, Owen Rowland, and Isabel Molina. 2014. Extracellular lipids of Camelina sativa: Characterization of chloroform-extractable waxes. Phytochemistry, 106: 188-196.

Dylan K. Kosma, Jahadeswar Murm, Fakhria M. Razeq, Patricia Santos, Richard Bourgault, Isabel Molina, and Owen Rowland. 2014. AtMYB41 Activates Ectopic suberin Synthesis and Assembly in Multiple Plant Species and Cell Types. The Plant Journal, 80(2):216-29.

Isabel Molina and Ruckus Franke. 2013.Biosynthesis of Suberin Polyesters. In: Acyl-lipid Metabolism, The Arabidopis Book, Rockville, MD: American Society of Plant Biologists. ISSN: 1543-8120. Gene database: http://aralip.plantbiology.msu.edu/pathways/pathways.

Dylan K. Kosma, Isabel Molina, Mike Pollard, John B. Ohlrogge. 2012. Identification of an Arabidopsis Fatty Alcohol:Caffeoyl-Coenzyme A Acyltransferase Required for the Synthesis of Alkyl Hydroxycinnamates in Root Waxes. Plant Physiology, 160, 237-248.

Isabel Molina. 2010. Biosynthesis of plant lipid polyesters. In: The Lipid Library, http://lipidlibrary.aocs.org/,The American Oil Chemists Society, Editor-in-Chief: Alejandro Marangoni.

Hua Weng, Isabel Molina, Jay Shockey, and John Browse. 2010. Organ fusion and defective cuticle function in a lacs1 lacs2 double mutant of Arabidopsis. Planta, 231: 1089-100.

Isabel Molina, Yonghua Li-Beisson, Fred Beisson, John Ohlrogge, and Mike Pollard. 2009. Identification of an Arabidopsis Feruloyl-CoA Transferase Required for Suberin Synthesis. Plant Physiology, 151: 1317-1328.

Isabel Molina, Katrin Weber, Déborah Y. Alves Cursino dos Santos, and John Ohlrogge. 2009. Transformation of a dwarf Arabidopsis mutant illustrates gibberellin hormone physiology and the function of a Green Revolution gene. Biochemistry and Molecular Biology Education, 37(3): 170-177.

Isabel Molina, John Ohlrogge, and Mike Pollard. 2008. Deposition and localization of Lipid polyesters in developing seeds of Brassica napus and Arabidopsis thaliana. The Plant Journal, 53: 437-49.

Isabel Molina, Ariana Circosta, Maria Cristina Añón, and Silvana Petruccelli. 2008. Mature Amaranthus hypochondriacus seeds contain non-processed 11S precursors. Phytochemistry, 69:58-65.

Yonghua Li, Fred Beisson, Abraham J.K. Koo, Isabel Molina, Mike Pollard, John Ohlrogge. 2007. Identification of acyltransferases required for cutin biosynthesis and production of cutin with suberin-like monomers. Proceedings of the National Academy of Sciences USA, 104:18339-18344.

Isabel Molina, Gustavo Bonaventure, John Ohlrogge, Mike Pollard. 2006. The lipid polyester composition of Arabidopsis thaliana and Brassica napus seeds. Phytochemistry, 67: 2597-2610.